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Bextra Side Effects

Name: Bextra
Generic: Valdecoxib

Manufacturer: Pfizer, Inc.
Date approved: November 2001
Status: Voluntarily withdrawn by manufacturer
Approved uses: Treating symptoms of osteoarthritis and rheumatoid arthritis in adults and in relieving painful menstrual cycles

Off-Label uses: General pain relief
Side effects:
  • Increased risk of cardiovascular events including heart attack and stroke when used in conjunction with non-steroidal anti-inflammatory drugs (NSAIDs).
  • Stevens-Johnson syndrome - a rare, sometimes fatal skin disease
Related topics: Unsafe Drugs, Stevens Johnson Syndrome
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Bextra Lawsuit Information

Bextra, or valdecoxib, is an anti-inflammatory drug used to treat symptoms of osteoarthritis and rheumatoid arthritis and to relieve painful menstrual cramps. Pfizer voluntarily withdrew Bextra from the market in 2005, after use of Bextra was shown to increase the risk of cardiovascular events, including heart attack and stroke. Bextra has also been linked to Stevens-Johnson syndrome, a sometimes fatal skin disease. SJS causes painful blistering and erosion of skin, rashes, and selling of skin and mucous membranes.

Pfizer Respectfully Disagrees with FDA Decision on Bextra

In April 2005, the Federal Drug & Food Administration (FDA) asked Pfizer Inc. to suspend sales of Bextra. Bextra is in the same class of drugs as Merck & Co's drug Vioxx, the COX-2 inhibitor pain reliever whose withdrawal from the market in September 2004 started the analysis of patient signals that Vioxx, like Bextra, caused increased rates of heart attacks and strokes in some people who took the medication. read more

Bextra Still Off the Market

Bextra®, generic name Valdecoxib, is a prescription COX-2 selective non-steroidal anti-inflammatory drug (NSAID) manufactured by Pfizer, Inc . On April 7, 2005, the Federal Drug & Food Administration (FDA) asked Pfizer to suspend sales of Bextra and to withdraw the drug from all markets due to adverse Bextra side effects. The FDA convened a public advisory committee meeting in February 2005 to review the cardiovascular safety of all COX-2 inhibitors and related drugs. read more

View the Bextra Law Articles page here

Bextra Jury Verdicts

______ $526,801 remitted to $369,507. Breakdown: $225,000 for pain and suffering; $34,702 for past medicals; $5,385 for past wage loss; $261,714 for future medicals; and $0 for future wage loss. - Soft Tissue Crush Injuries Yield $526,801 Verdict

______ VERDICT - MEDICAL MALPRACTICE - ALLEGED FAILURE TO PROPERLY MONITOR BLEED TIMES AFTER PRESCRIBING COUMADIN - INTERCRANIAL BLEED - WRONGFUL DEATH AT AGE 81.

View the Bextra Jury Verdicts page here

Bextra Videos

Information about Bextra Lawsuits

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Bextra FDA Information

CDER NME Approvals in Calendar Year 2001

Alert for Healthcare Professionals: Valdecoxib (marketed as Bextra)

View the Bextra FDA Information page here

Bextra News Articles

Glenmark Plans New Type Of Pain Killers

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View the Bextra News Articles page here

Bextra Newsfeeds

Inhibitex completes INX-189 Phase1a trial for HCV

NSAIDs Interfere With Tissue Healing

View the Bextra Newsfeeds page here

Bextra Patents

Substituted isoxazoles for the treatment of inflammation

View the Bextra Patents page here

Bextra Useful Web Sites

James F. Humphreys, LC, Bextra

Anapol Schwartz, Bextra Attorneys

View the Bextra Useful Web Sites page here

Bextra Wikipedia

Valdecoxib

Osteoarthritis

View the Bextra Wikipedia page here

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